Research from the University of Virginia Cancer Center have found that disrupting the microbiome of mice caused hormone receptor-positive breast cancer to become more aggressive and spread more quickly. "When we disrupted the microbiome's equilibrium in mice by chronically treating them (with) antibiotics, it resulted in inflammation systemically and within...

A new study confirms that the whole-genome approach for predicting heart disease in people who have never had a heart attack works and can be used in populations other than the ones used to develop them. The methods involve calculating a polygenic risk score (PRS) based millions of variants...

By Cindy Perettie, CEO, Foundation Medicine The way ASCO started for me this year set the scene for what was an inspiring and fascinating weekend. Early on Friday morning, before most people’s ASCOs had started, I sat in a meeting room in the conference center watching it slowly fill to...

The transfer of human microbiota to mice has successfully transplanted phenotypes of obesity, depression, Parkinson’s disease, schizophrenia, and multiple sclerosis. Now, we can add autism spectrum disorder (ASD) to the list. A new study suggests that the gut microbiome and its metabolites contribute to hallmark ASD behaviors and associated...

Medidata has announced the launch of Acorn AI to provide actionable data insights across the entire precision medicine lifecycle—from R&D to commercialization. Built unpon the Medidata platform, Acorn AI is fueled by one of the largest regulatory-grade clinical data repositories in the world, comprising more than 17,000 clinical trials...

LabCorp’s Integrated Oncology specialty laboratory announced it added therascreen PIK3CA PCR mutation analysis, a new companion diagnostic from QIAGE. The CDx identifies postmenopausal women and all men with hormone receptor positive, human epidermal growth factor receptor-2 negative (HR+/HER2-), PIK3CA-mutated, advanced or metastatic breast cancer who could benefit from the...

A genome-wide association study GWAS, headed by a team at the University of Oxford, U.K., and involving thousands of children in the U.K. and the Netherlands, has linked a number of genetic variations with the level of protective antibodies generated following routine childhood immunizations. The scientists say that with...

The Association for Molecular Pathology (AMP) said today it has expanded its set of conditions it wants to see met before it will support a clinically meaningful consumer genomic test. In an updated statement, AMP said its expanded set of conditions are intended to reflect the range of currently available...

More than 67 actionable clinical discoveries were made through deep longitudinal genomic analysis by a group led by Michael Snyder, MD, chair of the genetics department at Stanford University. The Stanford group’s pioneering precision health study is published in the May issue of Nature Medicine. To carry out the study,...

The most common bacterial cause of pneumonia around the world, Streptococcus pneumoniae,has been mapped by an international collaboration led by scientists from the Wellcome Sanger Institute, Emory University, and the U.S. Centers for Disease Control and Prevention. The Global Pneumococcal Sequencing Project (GPS) found 621 strains of the bacterium across...