One of the deadliest cancers, small cell lung cancer tends to spread early and aggressively with two-thirds of cases already metastatic at diagnosis while chemotherapy typically is not very effective at treating the disease.
Researchers discovered that bumetanide—used for more than 30 years to treat fluid retention associated with conditions like hypertension and heart failure—reverses signs of Alzheimer's disease in mice, as well as in human brain cells.
There is a pervasive concern in many industries that compliance with changing environmental regulatory directives will create an undesirable trade-off between health and safety and efficacy. As with other chemical substitutions, biocide preservatives for diagnostic assays do not reduce performance.
Seattle-based cell therapy biotech Immusoft has scored its first big pharma deal with Takeda and will partner to develop cell therapies for rare neurometabolic diseases that can traverse the blood brain barrier.
The method employs machine learning to aid in mapping the biochemical composition of tumors, and changes in the tumor microenvironment, from immunotherapy.
Despite differences in case collection, sequencing methods, and bioinformatics pipelines across all sites, Fabric GEM ranked the causative variant first or second more than 90% of the time in a new study, which included 119 Rady patients, mostly NICU infants, with rare genetic diseases.
The Qatar Genome Program has published an analysis of more than 6000 Qatari genomes, which researchers plan to use to improve the precision medicine offering in this region and discover insights into ancient population movements.
The Center for Admixture Science and Technology (CAST) will use the largest genomic datasets of individuals with diverse ancestry, in combination with socioeconomic data, to better predict health and disease in admixed individuals.
Test results will be available to patients and their treating health care providers to guide therapeutic decisions, advance cancer research, and support the development of new diagnostic tests and therapies for cancer treatment.
Analysis showed that people carrying the AD-associated mutation had lower structural connectivity in the frontoparietal control network, which connects areas mainly in the parietal and frontal lobes, two regions known to be involved with Alzheimer’s disease.
Recent success stories bring hope that long-read sequencing may make diagnosing rare genetic disease more successful.
Hailing from all corners of the globe, our 2021 list of influential women in precision medicine are scientists in the C-suite influencing the direction of the companies they help lead.
The COVID-19 pandemic saw a rush of companies developing diagnostics for the infectious disease that should benefit the detection of other diseases.
Artificial intelligence is emerging from its overhyped past to provide analytical muscle in precision medicine.
FDA, some experts at odds over agency’s accelerated approval for Aduhelm, the Alzheimer’s disease drug from Biogen and Eisai.