“Warp Speed” Plows $2.1B into Supporting Sanofi, GSK COVID-19 Vaccine Trial

The Sanofi-GSK vaccine combines Sanofi’s S-protein COVID-19 antigen, which is based on recombinant DNA technology, and GSK’s pandemic AS03 adjuvant.
Antibodies responding to coronavirus particles, illustration

Columbia Team ID Potent SARS-CoV-2 Antibodies to Neutralize the Virus

The team reported the isolation of 61 SARS-CoV-2-neutralizing monoclonal antibodies from five infected patients hospitalized with severe disease. Among these are 19 antibodies that potently neutralized the authentic SARS-CoV-2 in vitro, nine of which exhibited exquisite potency.
Killer T-lymphocyte attacking a cancer cell

Cancer Immunotherapy May Not Worsen COVID-19 Symptoms

Patients with cancer are at increased risk for developing severe COVID-19 and clinicians were concerned that continuing to treat these patients with cancer drugs that activate the immune system, such as immune checkpoint inhibitors, could make symptoms of the virus worse by increasing cytokine production.
Thrombus, illustration

RNA-Seq Shows Thrombotic Complications in COVID-19 Patients Linked to Platelet Hyperreactivity

The research team’s findings suggest that inflammatory proteins produced during COVID-19 infection make platelets hyperreactive and likelier to form blood clots via platelet to platelet and platelet to leukocyte interactions.

Genetic Variants Could Predispose Carriers To More Serious COVID-19 Infections

The researchers found that population distribution of the disease-associated genetic variants differed depending on a person’s ethnic origin. Some of the variants in the ACE2 gene were linked to cardiovascular and lung conditions, whereas some in the TMPRSS2 gene were linked to different cancers.

Data-Driven Precision Oncology Solutions

Sema4 Signal is a family of products and services providing data-driven precision oncology solutions with advanced analytics, digital tools, and exome-based somatic and hereditary cancer genomic tests.
Doctor holding Coronavirus vaccine. COVID 19 concept

Moderna’s COVID-19 Vaccine Speeds to Phase III Trial After More Positive Data

Moderna disclosed plans for the Phase III trial on Clinicaltrials.gov the same day that researchers from NIAID, Moderna, and their clinical research partners reported that mRNA-1273 induced rapid and strong immune responses against SARS-CoV-2, in an interim analysis of results from their Phase I study.
Antibodies responding to covid-19 coronavirus, illustration

Promising New Rapid COVID-19 Serological Test Data Released

Scientists in Singapore and China validated the test across two patient cohorts, with a sample size of 250 from China and 375 from Singapore, and found it achieved 99.93% specificity and 95–100% sensitivity and differentiated antibody responses to several human coronaviruses.

Newer, Dominant SARS-CoV-2 Variant Three to Six Times More Infectious than Previous Dominant Variant

Besides addressing the question of infectivity, the new research presents geographic information about the rise of the new variant, G614, and the relative decline of the previously dominant variant, D614, across the globe.
Portrait of woman holding black and white younger photo of herself

Pooled Genome-Wide Data Analysis Finds Link Between Blood Iron Levels and Aging

The study combined genome-wide association summary statistics for heart disease, dementia, and cancers and identified 10 genomic loci that appear to influence all three of those phenotypes.
male scientist pipettes in lab

CRISPR Comes of Age—As a Diagnostic

Hailed for its gene editing power, Sherlock Bioscience’s COVID-19 diagnostic is the first CRISPR technology to gain FDA approval.Hailed for its gene editing power, Sherlock Bioscience’s COVID-19 diagnostic is the first CRISPR technology to gain FDA approval.
At Home Coronavirus Test

Five COVID-19 Test Developers to Watch

The coronavirus pandemic compels diagnostics companies to bring new assays, technologies to market.

’Omics in Translation

Proteomics and metabolomics may lag behind genomics in providing clinically actionable insights today, but the future is bright.
cloud ocmputing

Six Precision Medicine Companies Making Their Mark in 2020

This year’s list of innovative companies have all found, or developed, technology solutions that have allowed them to become innovators in their niche.
DNA, doctor using tablet

Keeping up with the Genomes

Molecular diagnostics providers seek ways to maintain services in a world consumed by COVID-19.
Scroll Up