PRS Only Marginally Better than Established Methods of Predicting Heart Disease

While the results showed a strong association between polygenic risk scores and CHD, with those scoring highest on this calculator at baseline most likely to experience cardiac events over the follow-up period, the results were roughly the same using the ACC/AHA calculator.
Unrecognizable businessman having chest pain and heart attack

PRS Only Marginally Better than Established Methods of Predicting Heart Disease

While the results showed a strong association between polygenic risk scores and CHD, with those scoring highest on this calculator at baseline most likely to experience cardiac events over the follow-up period, the results were roughly the same using the ACC/AHA calculator.
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The Biomarker Future is Digital

As demand continues to grow for more data to inform precision medicine, digital biomarkers represent a new class of biomarkers that provide information in real time.
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Potency Assays for Cell and Gene Therapy

Polygenic risk scores deliver a more precise estimation of individualized risk of developing a disease, with heart disease and cancer leading the way.
Personalized Medicine Conference panelists

Moving the Diagnostics Needle for Personalized Care

A panel discussion at the Personalized Medicine Conference last year lays out the case for developing clinical data to speed personalized healthcare
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Dawn of the Customized Cure

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Looking Ahead to 2030

While much progress has been made, it is fair to say more advances are needed before precision medicine and/or genomic medicine is standard practice. So how will we get there? Read on as four industry watchers share with you their thought on what may happen in the next ten years to advance the field.
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Coronavirus: What We Know Today and Where Do We Go from Here

Illumina’s Staff Product Manager of Infectious Disease Michael Oberholzer, Ph.D., and Chief Medical Officer Phil Febbo, M.D., offer their perspective on the novel Coronavirus SARS-CoV-2 (2019-nCoV) outbreak.
Delicious Mediterranean Appetizer from directly above.

Mediterranean Diet Improves Gut Microbiome, Promotes Healthy Aging

A five-country study found that eating a Mediterranean diet for a year boosts the types of gut bacteria linked to “healthy” aging while reducing those associated with harmful inflammation in the elderly.

Triple negative breast cancer might not actually be ‘breast cancer’

The study could signal a potential treatment breakthrough for patients with this form of breast cancer, which disproportionately affects and tends to develop more aggressively in black women.
Unrecognizable businessman having chest pain and heart attack

PRS Only Marginally Better than Established Methods of Predicting Heart Disease

While the results showed a strong association between polygenic risk scores and CHD, with those scoring highest on this calculator at baseline most likely to experience cardiac events over the follow-up period, the results were roughly the same using the ACC/AHA calculator.

Small Sequencer Developer GenapSys Completes $90M Series C Financing

GenapSys’ sequencing system is about the size of an iPad, costs under $10,000, and is based on a proprietary direct electronic sequencing chip, which is intended to eliminate the need for cumbersome equipment.

Takeda Invests in Patient-Centric Health Data Company Seqster

The investment allows Seqster to ramp up development of its technology which streamlines patient recruitment for clinical trials by matching consenting patients based on their EHR, genomic, and real-time digital data delivered by wearable monitoring devices.
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Researchers Detail Mechanism for Clearing Misfolded Proteins at Root of Alzheimer’s Disease

The chaperone protein Clusterin shuttles misfolded proteins directly into cells for degradation, a finding that could point to new therapeutic targets for AD and other neurodegenerative diseases.
CellMax Life's CMxTM circulating tumor cell (CTC) platform and liquid biopsy panel will be used by Medigen Biotech in upcoming clinical trials of its cell therapy candidates for cancers

New Liquid Biopsy Method IDs Melanoma Patients Likely to Relapse

Although CTCs can be detected in melanoma patients, there is limited data regarding their significance in stage III (node-positive) disease. This prospective study was based on earlier studies that found CTCs in a significant number of breast cancer patients was associated with relapse, independent of other prognostic methods.
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Alternative Splicing Identified as a Potential Driver of Aggressive Cancers

The researchers developed new computational tools and biological model systems to study the link between a strong cancer driver gene that impacts changes in proteins related to alternative splicing regulation.
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8 Companion Diagnostic Developers Making a Mark

If companion diagnostics (CDx) were people, they would be old enough to drink. The first CDx won FDA approval in 1998, when Dako Denmark (since acquired by Agilent Technologies) received authorization to market HercepTest. The immunohistochemistry (IHC) assay was designed to detect human epidermal growth factor receptor 2 (HER2)...

From Bench to Clinic—The Potential of New Sequencing Tools

Sponsored content brought to you by As genome sequencing technology advances, researchers are increasingly exploring emerging tools for a host of potential clinical applications. Andrew...

Mainstreaming Precision Oncology

Sponsored content brought to you by   What if every patient’s oncologist or lab testing personnel had access to an online digital encyclopedia of cancer mutations,...

Better Understanding of Post-Translation Modifications Driving Innovation

Sponsor: The age of mainstream social media is upon us and everyone now has multiple avenues to become an influencer and to change the status...
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