DNA Binary

Language Algorithms Shed Light on How Viruses Like SARS-CoV-2 Mutate to Avoid Immune System

The researchers trained a natural language processing model to analyze patterns found in genetic sequences, which allowed it to predict new sequences that have new functions but still follow the biological rules of protein structure.
Triple negative breast cancer cell undergoing retraction and apoptosis

Researchers Activate Antiviral Immune Pathways in Triple Negative Breast Cancers

The study shows that endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.
Epic Sciences is partnering with four Canadian breast cancer centers to carry out a clinical validation trial of the company’s blood test

Mutations in Gene Linked to Acute Myeloid Leukemia Can Drive Other Blood Disorders

Research explains how mutations in the RUNX1 gene, which encodes a protein that guides the way hematopoietic stem cells change into adult blood cells, can influence blood cell development and cause different types of cancer and other blood disorders.
Healthcare: Medical students learn heart surgery procedure.

cfDNA Test Developed to Detect Acute Rejection After Heart Transplant

In studies of a group of 171 heart transplant recipients, the new blood test performed better than tissue biopsies, signaling problems even when no outward signs of rejection were evident.

Tandem Repeat Mutations Linked to Autism Spectrum Disorder

Tandem repeat mutations, found in non-coding areas of the DNA, could be linked to the presence of autism spectrum disorders, according to University of California researchers.

Biodesix, HiberCell Launch CDx Collaboration

Biodesix agreed to develop an enzyme-linked immunosorbent assay (ELISA) designed to assess cancer patients’ eligibility for treatment with HiberCell's Imprime PGG immunotherapy.
Glioblastoma brain cancer, CT scan

Low Tumor Mutation Levels Improve Response to Immunotherapy in Recurrent Glioblastoma

Having a low level of tumor mutation improves immunotherapy treatment response and survival time in patients with recurrent glioblastoma, suggests research led by Duke University.
How COVID-19 can damage the brain, the deterioration of myelin a fatty coating that protects neurons.

Neuroinvasion Mechanisms of SARS-CoV-2 Discovered

SARS-CoV-2 can affect many other organs in the body including the central nervous system, where the infection is associated with a variety of symptoms ranging from headaches and loss of taste and smell to impaired consciousness, delirium, strokes, and cerebral hemorrhage.

Pacific Biosciences, Invitae to Codevelop Clinical WGS Platform

Leveraging both Sanger sequencing and long-read technology , PacBio and Invitae will look to develop new whole-genome assays in areas such as carrier screening, immune system response, and other heritable diseases.
Inivata and Thermo Fisher Scientific are collaborating with Genomics England to assess the quality of blood plasma samples and explore the potential of liquid biopsy to improve disease management and patient outcomes. [Source: © Alex Tihonov/Fotolia]

Resolution Bioscience, Mirati Therapeutics Ink CDx Deal

Under the agreement, Resolution will leverage its ctDx liquid biopsy platform to identify patients who may benefit from Mirati’s investigation KRAS G12C inhibitor in the treatment of non-small cell lung cancer (NSCLC).
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