The researchers trained a natural language processing model to analyze patterns found in genetic sequences, which allowed it to predict new sequences that have new functions but still follow the biological rules of protein structure.
The study shows that endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.
Research explains how mutations in the RUNX1 gene, which encodes a protein that guides the way hematopoietic stem cells change into adult blood cells, can influence blood cell development and cause different types of cancer and other blood disorders.
In studies of a group of 171 heart transplant recipients, the new blood test performed better than tissue biopsies, signaling problems even when no outward signs of rejection were evident.
Tandem repeat mutations, found in non-coding areas of the DNA, could be linked to the presence of autism spectrum disorders, according to University of California researchers.
Biodesix agreed to develop an enzyme-linked immunosorbent assay (ELISA) designed to assess cancer patients’ eligibility for treatment with HiberCell's Imprime PGG immunotherapy.
Having a low level of tumor mutation improves immunotherapy treatment response and survival time in patients with recurrent glioblastoma, suggests research led by Duke University.
SARS-CoV-2 can affect many other organs in the body including the central nervous system, where the infection is associated with a variety of symptoms ranging from headaches and loss of taste and smell to impaired consciousness, delirium, strokes, and cerebral hemorrhage.
Leveraging both Sanger sequencing and long-read technology , PacBio and Invitae will look to develop new whole-genome assays in areas such as carrier screening, immune system response, and other heritable diseases.
Under the agreement, Resolution will leverage its ctDx liquid biopsy platform to identify patients who may benefit from Mirati’s investigation KRAS G12C inhibitor in the treatment of non-small cell lung cancer (NSCLC).