Happy couple lying down on the carpet and communicating.

Different Fat Gene Expression in Men and Women May Impact Disease Risk

A University of Virginia study discovered 162 genes in fat tissue that differ in the way they are expressed between men and women, which could impact disease risk.
Antibodies responding to covid-19 coronavirus, illustration

Severe COVID-19 Activates Specific Set of T Cells

New research corroborates other studies that highlight potential associations between strong MAIT cell activation and severe COVID-19 outcomes and provide important information to help better understand the immune response to SARS-CoV-2 that could help develop new treatments.
Berg will partner with Massachusetts General Hospital and Brigham and Women's Hospital to study potential biomarkers for Alzheimer's and other neurodegenerative disorders from Harvard Biomarker Study biospecimens. [Source: ajcity.net]

Epigenetic Drivers of Alzheimer’s Disease Identified

This new data suggests that Alzheimer’s disease involves a reconfiguration of the epigenomic landscape, with the marks H3K27ac and H3K9ac affecting disease pathways by disrupting the transcription- and chromatin-gene feedback loops.
CT scan image showing an abdominal aortic aneurysm

Abdominal Aortic Aneurysm Gene Variants Could Help Identify At-Risk Individuals

A study carried out in veterans has identified 14 new areas of genetic variation linked to risk for abdominal aortic aneurysms, which the researchers believe could help identify those at risk of experiencing these life-threatening cardiovascular events.
Bristol-Myers Squibb (BMS) plans to use Natera's Signatera custom circulating tumor DNA (ctDNA) assay in a Phase II study designed to assess the pharma giant’s cancer immunotherapy Opdivo (nivolumab) as an adjuvant treatment for non-small cell lung cancer (NSCLC). [Source: Eraxion/Getty]

Circular RNA Identified as Potential Drug Target for Lung Squamous Cell Cancer

A large number of researchers have demonstrated that circular RNAs are correlated with the pathogenesis of various human diseases, including nervous system disorders, cardiovascular disorders, Alzheimer’s disease, diabetes, cancer, and more.

COVID-19 Severity Tied to 13 Rare Genetic Variants

A significant number of people with severe COVID-19 carried rare genetic variants in 13 genes known to be critical in the body’s defense against influenza virus, and more than 3.5% were completely missing a functioning gene.
Alexander Fleming, who is credited with discovering penicillin in 1928.

Original Penicillium Mold Genome Could Point to New Routes for Industrial Manufacture

A study comparing the genome sequence of Alexander Fleming’s original Penicillium mold and the U.S. strain used for industrial penicillin manufacture today show the original uses slightly different mechanisms to produce penicillin, which could point to new routes for industrial production.
New research examines why some children born with heart defects also have developmental disabilities. [Image courtesy of Mark L. Riccio

New Cardiac Cell Atlas Could Fuel Personalized Heart Treatments

A detailed cellular and molecular map of the human heart has been created through a collaboration between several groups of scientists around the globe to improve understanding of its biology in both health and disease.
OraSure lab

Wide Variety in Accuracy of COVID-19 Antibody Tests Revealed

Researchers based at Kings College in London have discovered that commercially available antibody tests for COVID-19 vary widely in accuracy. The findings also revealed that some fast, lateral flow immunoassay tests, initially assumed to be less accurate, actually produced high quality results.
coronavirus,3d render

Large Phase III Trial Launched for J&J’s COVID-19 Vaccine

J&J’s Janssen has moved into Phase III with its single-dose COVID-19 vaccine candidate, which it plans to test in up to 60,000 study participants in eight countries, to evaluate its safety and efficacy compared with placebo.
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