Close-up of male eye with round HUD display

Newly-Identified B-Cell Subset Reduces Chronic Inflammation

Scientists report they have identified, isolated, and characterized a unique population of B cells that tamps down the immune system, reducing chronic inflammation. Their work suggests the cells may play a role in future human therapies.
Blood Test Results In A Medical Lab

Blood-Test for HPV-Related Head and Neck Cancer Developed

With HPV-associated head and neck cancer rates on the rise, there is a great need for more accurate, less-invasive, faster and less expensive diagnostic tests, according to authors of a new study.
Pancreatic cancer, malignant tumor of pancreas

Rheumatoid Arthritis Drug Candidate Aids Chemotherapy for Pancreatic Cancer

New research indicates that an investigational anti-inflammatory drug in clinical trials for RA, ATI-450, may also reduce some of the damaging side effects of the chemotherapy cocktail FOLFIRINOX (a combination of folinic acid, 5-fluorouracil, irinotecan and oxaliplatin), which is commonly used to treat pancreatic cancer.

Sponsored: Controlling Variabilities in Liquid Biopsy

Cell free DNA formulated in synthetic matrix that is compatible with diverse extraction platforms provides greater flexibility in choosing reference materials.
Image to signify drugs designed by artificial intelligence.

Insilico Medicine Brings First AI-Designed Drug to Clinical Trials

Insilico Medicine brings first AI designed and created drug candidate for idiopathic pulmonary fibrosis to human trials in less than 3 years and with preclinical costs of only $2.6M.
Cognoa's artificial intelligence-based software platform for behavioral health conditions has received the FDA’s Class II diagnostic medical device designation for autism. [© ktsdesign/Fotolia]

ANK2 Gene Variants Linked to Autism Shown to Alter Neuronal Architecture.

Multiple genetic studies have consistently identified rare variants in ANK2 in individuals with ASD, making it one of the high-confidence risk genes associated with the condition.
Human heart with bronchial tree, illustration

Diabetes Medication Improves Outcomes for Heart Failure Patients

SGLT2 inhibitors are approved to treat type 2 diabetes, and their main mechanism of action is to block reabsorption of glucose in the kidney, but these drugs also have potential to treat heart failure patients, suggests new research.
Acute lymphoblastic leukaemia, illustration

Sequencing Superior for Acute Lymphoblastic Leukemia Relapse Prediction

In pediatric and young adult patients with acute lymphoblastic leukemia treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease identified all patients who would eventually relapse, and was more accurate than flow cytometry.
Young man working at home

Agena Biosciences, Manchester University Partner on Pharmacogenomics Education

Under the terms of the partnership, Agena Bioscience will promote to its customers the established MU PGx programs, including the Graduate Certificate in PGx or Master of Science in PGx degree. Both programs are fully online and delivered by Manchester University faculty.
Metastatic breast cancer

Partial and Full Epithelial-Mesenchymal Transition Play Varied Roles in Cancer Metastasis

Not all cancer cells go through the epthelial-mesenchymal transition program in full, which is why they ultimately have different characteristics and properties.