Doctor reading test results

Breast Cancer Care After Genetic Testing Often Doesn’t Follow Guidelines

Tracking treatment trends is important as more women are receiving genetic testing when they are diagnosed with early-stage breast cancer and treatment options are expanding.

Research Reveals 28 New Genes Associated with Rare Developmental Disorders

Research led by the Wellcome Sanger Institute near Cambridge, UK, has identified 28 new genes that are associated with developmental disorders in children, which could lead to diagnoses for around 500 families.
Secondary tuberculosis infection, illustration

Gene Expression Blood Test Predicts Tuberculosis Onset

The researchers’ studies indicated that eight different transcript signatures, regulated by interferon signaling, demonstrated equal accuracy for diagnosing incipient tuberculosis.
Congenica and FutureNeuro will partner to develop new software designed to deliver faster and more accurate diagnoses in some genetic epilepsies. [P. Moghe

Congenica, FutureNeuro to Partner on Software for Some Genetic Epilepsies

FutureNeuro will use Congenica’s clinical genomics analysis software Sapientia to study mutations seen in 40% of childhood epilepsies
Source: Cancer.gov

Triple Negative Breast Cancer Biomarker Predicts Poor Prognosis for African Americans

Racial disparities in disease, particularly breast cancer, continue to pose a major challenge in healthcare.

Invivoscribe Expands into Drug Development with Domainex Licensing Deal

Invivoscribe says it aims to accelerate drug development by combining with the company’s in-house expertise in diagnostics development and worldwide access to patients and clinical testing capabilities.

AstraZeneca Launches Genomics Initiatives with HLI, Sanger, and FIMM

Human Longevity Inc. will sequence and analyze up to 500,000 DNA samples from patients in AstraZeneca clinical trials over 10 years.

New Fluorescence-Based COVID-19 Test is Quick and Easy

The “one-pot” assay uses fluorescence-based detection of RNA from pathogens, can be performed within 30–50 minutes of incubation time, and can reach a limit of detection of 0.1-attomolar RNA concentration.
Doctor holding Coronavirus vaccine. COVID 19 concept

Phase I COVID-19 Vaccine Data from Moderna Shows Immunogenicity in Older Patients

mRNA-1273 was shown to induce CD4+ T-cells of the Th-1 phenotype 14 days after the second dose was given. Th1-biased CD4+ T-cell response was seen across all age groups, as were rare Th2 phenotype responses.

Synthetic Protein Could Be Effective COVID-19 Treatment

The ability to generate high-affinity Spike protein binders that block viral interaction with ACE2, but which are highly stable, and small—“to maximize the density of inhibitory domains”—could have multiple advantages over antibodies for direct delivery into the respiratory system.
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