Guardant360 Gets Expanded LCD for Broad Swath of Solid Tumor Cancers

The coverage decision from Palmetto GBA includes all fee-for-service Medicare patients with advanced cancers who meet its clinical criteria for genomic profiling to help select the most appropriate treatment, but don’t have tissue samples for molecular profiling.
Coronavirus spike protein and receptor, illustration

Research May Explain Why Men Are More Susceptible to COVID-19 Than Women

COVID-19 infects cells by binding to the ACE2 protein, found on the surface of cells in the lungs, cardiovascular system, kidneys, and in the gut. The research says the biggest predictor of high ACE2 levels is being male.
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Gut Microbiome Bacteria Provides Link Between Fiber and Heart Health

Researchers show that mice harboring the butyrate-producing bacteria Roseburia eating a high-fiber diet suffered from less atherosclerosis
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Keeping the Beat

Researchers Find New Genetic Variants Linked to Atrial Fibrillation, Suggesting New Treatment Targets
Most cases of colorectal cancer evade early detection

FDA Expands Cologuard Cancer Test Approval to Younger People

Exact Sciences announced  that the U.S. Food and Drug Administration (FDA) approved its noninvasive colorectal cancer screening test, Cologuard, for eligible average-risk individuals ages...
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Thermo Fisher Lists Its Ion PGM DX System as Class II Clinical Medical Device

Thermo Fisher Scientific completed the listing of its Ion PGM Dx next-generation sequencing (NGS) system with the FDA for clinical use as a class...
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VISTA Molecule a Target for Pancreatic Cancer Immunotherapy

The immune checkpoint molecule could represent a promising target for pancreatic cancer, one of the deadliest and hardest to treat cancers
“Just the place for sequencing a Snark!  I have sequenced it twice: That alone should encourage the crew. Just the place for sequencing a Snark! I have sequenced it thrice: What I sequence three times is true.” —	Adapted from The Hunting of the Snark (An Agony

Comparison of Whole-Genome Sequencing Strategies for the Detection of Somatic Mutations in Cancer

The rapid advancement of NGS in clinical diagnostics underscores the need for more assay standardization.
Medical bottle with hydroxychloroquine HCQ pills, 3D rendering isolated on white background

Pharmacogenetics Research for COVID-19 Drugs Needed to Improve Patient Safety

Most drugs used for COVID-19 treatments are not being used for the indication they were originally designed for and there has been much public debate about how effective or safe some of them are.
Haploid human embryonic stem cells created at the Hebrew University's Azrieli Center for Stem Cells and Genetic Research. [Hebrew University of Jerusalem]

CRISPR Screens Stem Cell Genome, Charts Essentialome

Leveraging CRISPR-Cas9 scientists generate an atlas of genes essential for the normal growth and maintenance of human pluripotent stem cells
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