Alzheimer: Phosphorylation of Tau proteins leads to disintegration of microtubuli in a neuron axon

Alzheimer’s DNA Methylation Study Uncovers 84 New Genes Associated with the Disease

The meta-analysis, believed to be the largest of its type, reviewed six earlier DNA methylation studies of AD, which represented brain tissue studies of 1,453 individuals.
Colon cancer. Cancer attacking cell. Colon disease concept

More Evidence Found of Colon Cancer’s Link to a High-Fat Diet

The researchers examined the proposed link between peroxisome proliferator-activated receptor (PPAR) and how it promotes regeneration and tumorigenesis by enhancing intestinal stem cell numbers, proliferation, and function.
Vials With the Covid-19 Vaccine and Syringes are Displayed On a Tray at the Corona Vaccination Center

New Study Shows COVID-19 Vaccine from J&J Is Effective Against Variants of Concern

In the three months since J&J’s COVID-19 vaccine received emergency use authorization from the FDA, more than 10 million Americans have received the vaccine, according to the Centers for Disease Control and Prevention.

Sponsored: Making NGS Actionable—Moving Oncology Beyond ‘One Mutation-One Drug’

While most NGS providers limit their annotated reports to one mutation-one drug associations that address targeted therapeutics, Cellworks’ biosimulation platform permits an assessment of all cancer therapies, including radiation, chemotherapy, and immunotherapy.
Breast cancer cells, SEM

Potential Treatment Option for Some Patients with Triple Negative Breast Cancer Discovered

Inhibition of the NAMPT enzyme pushes triple negative breast cancer cells towards apoptosis and adding compounds that block anti-apoptotic proteins ensures cancer cell death, presenting a new treatment opportunity for these patients.
Woman injecting insulin, daily diabetes care during COVID-19

Early Changes in Gene Expression Observed Pre-Diagnosis in Type 1 Diabetes

Research shows that abnormal gene expression changes can occur before islet autoimmunity or type 1 diabetes is present in susceptible children, which could help predict who is most likely to progress to full-blown diabetes.
NGS technology has enabled researchers to epidemiologically analyze DNA sequences by quickly deciphering mass quantities of genetic information in a short amount of time. [Heart illustration: iStock/SvetaP DNA double helix: iStock/Kagenmi]

Study Supports Link Between SORBS2 and Congenital Heart Disease

To explore the potential role of SORBS2 in congenital heart disease, researchers suppressed the gene in developing human heart cells grown in the laboratory. This led to the development of abnormally shaped heart cells and interfered with the ability of cardiac muscle cells to undergo necessary changes in gene expression.
People walking through airport, silhouette (focus on aeroplane)

Antimicrobial Resistant Superbugs Spread via Microbiomes of International Travelers

Poverty, poor sanitation, changing agricultural practices and overuse of antibiotics in people and livestock have turned many developing regions into hot spots for diseases spread by bacteria, including infections that are increasingly resistant to a range of antibiotic drug treatments.
Young man having stomach ache, painful area highlighted in red

Adding Gut Microbe Shows Promise in Reducing Colitis Risk

Researchers at the University of Chicago show that replacing just one species of a microbe—Bacteroides sp. CL1-UC (Bc)—to the gut microbiome at a specific developmental phase of the disease can prevent antibiotic-induced colitis in a mouse model of the condition.
Lymphocytes, illustration

Pathogen Orientation Key to T-Cell Therapy Activation

A recent study by an international team of researchers has found that T cells need to recognize pathogens in a particular orientation in order to receive a strong activating signal.

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