Colon cancer, light micrograph

Biomarker-Informed Treatments for Gastric Cancer Patients Improve Outcomes

Use of a highly personalized approach to treatment including specific monoclonal antibodies tailored to a patient's biomarker profile improves outcomes for patients with metastatic gastroesophageal cancers, shows research from the University of Chicago.
coronavirus

Genomic Applications in the Fight against SARS-CoV-2

In this Keynote Webinar, sponsored by Illumina, two leading researchers will show how genomic technologies are tackling the COVID-19 pandemic—Alex Greninger, MD, PhD, (University of Washington School of Medicine) and Darrell Dinwiddie PhD, (University of New Mexico Health Sciences Center).
Scientists conducting the process of Polymerase chain reaction (PCR) to amplify DNA by using a thermocycler to create samples

Thermo Fisher to Buy POC Molecular Dx Provider Mesa Biotech

Mesa Biotech has developed and commercialized a PCR-based rapid point-of-care testing platform available for detecting infectious diseases including SARS-CoV-2, Influenza A and B, respiratory syncytial virus (RSV) and Strep A.
Human kidney cross section on scientific background

Triple Therapy Approach for Renal Cell Carcinoma Shows Promise

Experiments in preclinical models of RCC showed that triple therapy using established treatments plus angiotensin-(1–7) can improve tumor response and significantly prolong survival, suggesting that bolstering ACE2 could improve how patients respond to VEGFR inhibitors, which often lose their effectiveness against cancers over the long term.
Asian doctor in PPE medical suit with an injection vaccine and infusion drip for covid-19 or corona virus patient

Trial Suggests Arthritis Drug Has No Benefits for COVID-19 Patients

Despite previous findings to the contrary, the randomized controlled trial, carried out at the Beneficência Portuguesa Hospital of São Paulo, Brazil found that adding tocilizumab to standard care appeared to increase rather than decrease deaths in COVID-19 patients, leading to the trial being stopped early.
Researchers at The University of Texas MD Anderson Cancer Center have found that a rare resistance mutation first thought to appear in melanoma (pictured) following treatment with a targeted therapy has instead turned out to be hiding in the tumor all along. [Definiens]

Melanoma Vaccine from NeoVox Shows Anti-Tumor Response Four Years Later

In a Phase 1 study among eight patients with advanced melanoma who received the NeoVax vaccine, after a median of four years, all of the patients remained alive and six patients had no signs of active disease.

Lilly and Merus Join Forces to Develop Bispecific Antibodies Against Cancer

Through its Biclonics platform, Merus aims to produce novel bispecific antibodies that are capable of binding two targets, but which neither require linkers or modifications to force correct pairing of heavy and light chains, nor require fusion proteins to add functionality.
Neuron system

Maltese ALS Patients Have Different Genetic Mutations than Northern Europeans

A study carried out by the University of Malta shows that patients with the fatal neurological condition amyotrophic lateral sclerosis have different causative mutations to patients from Northern Europe.

Syntegra, NIH, Gates Foundation Partner on COVID-19 Synthetic Patient Data

Syntegra uses machine learning to create validated “synthetic data”—replicas of healthcare data that are designed to precisely duplicate its statistical properties, with patient privacy protected by removing all links to the original data.
CRISPR technology

Mammoth, IDbyDNA Get DARPA Funds for CRISPR Diagnostics Development

DARPA identified five disease categories for which the devices should detect pathogens and biomarkers: respiratory illnesses, febrile illnesses, vector-borne illnesses, gastrointestinal illnesses, and sepsis.
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