Innovative Genomics Institute’s “pop-up” SARS-CoV-2 testing laboratory

Building a COVID-19 Pop-Up Testing Lab

Postdocs working in the lab of Jennifer Doudna at UC Berkeley bring the testing lab online in just three weeks.

FDA Approves First NGS-Based Liquid Biopsy Companion Diagnostic

The FDA has approved Guardant360 CDx for tumor mutation profiling in patients with any solid cancerous tumor and has also approved it as a CDx to identify non-small cell lung cancer patients with epidermal growth factor receptor (EGFR) alterations who may benefit from treatment with Tagrisso (osimertinib).
Unrecognizable businessman having chest pain and heart attack

Heart Disease Biomarker Captured by New Nanoparticle Technology

The new method, called nanoproteomics, captures and measures various forms of the protein cardiac troponin I, or cTnI, a biomarker of heart damage currently used to help diagnose heart attacks and other heart diseases.

Northwell Health Releases Data on COVID-19 Antibody Testing of its Frontline Staff

More than 40,000 HCPs consented to testing with 13% (5,523) testing positive for antibodies. The positive sample pool comprised 11,468 (28.4% of positive tests) and 3,746 physicians (9.3%).
Neuron system

Enzyme May Unlock New Huntington’s Disease Therapeutic Approach

The kinase enzyme, called TBK1, plays a central role in regulating the degradation and clearance of the huntingtin protein and introduces chemical modifications that block its aggregation.
remdesivir covid-19 liquid medication background

NIH Launches Remdesivir Plus Interferon Beta-1a Trial for COVID-19 Treatment

The study, called the Adaptive COVID-19 Treatment Trial 3 (ACTT 3), is anticipated to enroll more than 1,000 hospitalized adults with COVID-19 at as many as 100 sites in the United States and abroad.
Gut bacteria , gut flora, microbiome. Bacteria inside the small intestine, concept, representation. 3D illustration.

The Gut Microbiome Helps Determine B Cell and Antibody Repertoire

Custom computer programs processed millions of genetic sequences to compare the antibody repertoire from B cells, depending on whether the microbes stay in the intestine, or whether they reach the bloodstream. In both cases, the antibody repertoire is altered, but in rather different ways depending on how the exposure occurs.
Tumor profiling assays of Foundation Medicine and Caris Life Sciences will identify abnormalities qualifying a patient for personalized cancer treatment through NCI-MATCH. [Royalty Stock Photo/Shutterstock]

TRACK Study Seeks to Develop Precision Medicine Approaches for Rare Cancers

TRACK will recruit 400 people diagnosed with any rare cancer, which is defined as incidence of six per 100,000 people, per year, in the U.S. The study will focus on cholangiocarcinoma and cancer of unknown primary due to the promise of precision approaches in these subsets.
Freenome’s artificial intelligence (AI) genomics platform

AI Predicts Patient Phenotypes that Will Develop Drug Resistance

Findings from the new study could point to methods for identifying diseases and predicting their behaviors that are faster, simpler, less expensive, and more accurate than current standard techniques.

Gene Expression Signature in Blood Can Diagnose Brain Damage in Newborn Babies

Results from the early blood tests showed that those that had poor outcomes from oxygen deprivation during birth could be predicted based on changes in the expression of 855 genes in the blood shortly after birth.
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