ACE inhibitors and Angiotensin Receptor Blockers May Increase Mortality Rate In Elderly COVID-19 Patients
These highly prescribed medications change cell surface protein expression, which is particularly problematic in cells in the respiratory system—tissue that is vulnerable to targeting and attack by the COVID-19 virus.
Up-and-Coming Diagnostic Test Developers Emerge as Consolidation Thins the Field.
The studies showed that the drug, ivermectin, started to become effective against SARS-CoV-2 in lab-grown cells within just a day and “could essentially remove all viral RNA by 48 hours,” researchers said.
These ten governments have committed funding for projects that will sequence a minimum of 100,000 citizens to spur genomic medicine
If companion diagnostics (CDx) were people, they would be old enough to drink. The first CDx won FDA approval in 1998, when Dako Denmark...
10 privately-held diagnostics developers primarily focused on liquid biopsy tests, ranked by total money raised from venture capital firms.
Company expects to deliver 50,000 tests per day of the rapid, instrument-based, isothermal system designed for qualitative detection of infectious diseases.
Smokers, COPD Patients’ Increased Levels of ACE2 Receptors Make Them More Vulnerable to SARS-CoV-2...
SARS-CoV-2 uses the ACE-2 receptor as a cellular entry receptor, the authors wrote. While the virus can infect people of any age, most of the severe cases, to date, have been in individuals over the age of 55 years and with significant comorbidities, such as COPD.
The guidelines—based on published and preliminary data—are posted online at covid19treatmentguidelines.nih.gov and will be updated regularly as new data from peer-reviewed scientific literature and other authoritative information emerges.
Mechanisms that may increase COVID-19 susceptibility for diabetics include a higher affinity of cellular binding and efficient virus entry; decreased viral clearance in the blood stream; diminished T cell function; increased susceptibility to hyper-inflammation and cytokine storm syndrome; and the presence of cardiovascular disease.