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Strata Oncology to Offer Patient ID and Enrollment for Epizyme Trial of NHL Candidate

Deal leverages Strata Trial, a program to sequence 100,000 advanced cancer patients to expand patient access to clinical trials.
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Parallelized CRISPR-Cas9 Generates Sequence Variants Genome Wide

UCLA researchers modify technique previously used for gene inactivation so it can be used to introduce particular DNA sequences, or patches
Clinical OMICs Magazine: Volume 2

System-Wide Map of Genetic/Metabolomic Connections Released

If a genetic variant is the origin and a disease the destination, the biochemical path between them may appear on a map of a...
Bone cancer cell, SEM

Molecular Mechanisms of Osteosarcoma Provide Clues for Improved Immunotherapy Strategies

Poor infiltration of the tumor by immune cells, low activity from available T cells, a lack of immune-stimulating neoantigens, and multiple immune-suppressing pathways all combine to hinder response to immunotherapy.
Tumor - Cancer cells reproduction

Slowing Amino Acid Metabolism Curbs Tumor Growth

By restricting the dietary amino acids serine and glycine, which in turn targeted the serine synthesis enzyme phosphoglycerate dehydrogenase, the team induced tumor cells to produce a toxic lipid that slows cancer progression in mice.
Many more promoter interactions (purple arcs) are captured by the Capture Hi-C method (second track) versus the regular Hi-C method (first track). The interactions from a single promoter (third track) reach numerous other DNA segments

Culling Contacts from DNA’s Calling Records

Sift through metadata. Track contact activity. Identify suspicious patterns. This to-do list sounds as though it were devised by the National Security Agency. But...
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AZ Partners with DNAnexus for 2 Million Patient Sequencing Project

The 10-year partnership will see the companies develop a secure, cloud-based informatics environment for the ambitious research initiative
Increased scrutiny from the Office of Inspector General will force clinical labs to ensure that their practices are sound and their records complete. [WavebreakMediaMicro/Fotolia]

Uncle Sam Casts Wary Eye on Clinical Lab Billing

Washington will keep its eye on clinical laboratories this year—specifically, how much they are billing the federal government for services through Medicare. The U.S. Department...
Guardant Health has launched for research use LUNAR

Moonshot Sees Liftoff: Guardant Launches LUNAR Early Cancer Assay for Researchers

Blood-based test, designed to detect genomic alterations and epigenomic signatures, is set for clinical launch in the second half of 2019
Qiagen has rolled out an improved version of its Qiagen Clinical Insight (QCI) software that incorporates the AMP/ASCO/CAP Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer. [Source: © Mopic/]

Qiagen Integrates AMP/ASCO/CAP Variant Guidelines Into QCI-Interpret Solution

Qiagen launches improved version of its QCI-Interpret software incorporating AMP/ASCO/CAP guidelines for interpreting cancer variants
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