Molecular Dx

Sponsor: IlluminaIn this Clinical OMICs KEYNOTE webinar, sponsored by Illumina, we are delighted to host two true pioneers of clinical genome sequencing, bioinformatician Dr. Liz Worthey and geneticist Dr. Howard Jacob, who will reflect on a decade of progress in clinical genome analysis and discuss the future challenges confronting the field.

By analyzing the genomic sequences of SARS-CoV-2 samples from infected patients in Washington State, research suggests that most early infections derive from a single introduction in late January or early February, sparking rapid community transmission of the virus that went undetected for several weeks.

By combining available genome-wide association study data and applying mathematical weighting methods, the team found a PRS formula that appears to predict which patients may develop DILI as a result of taking different drugs.

The latest funding brings to $378 million the total value of contracts awarded to 16 developers of advanced COVID-19 diagnostics through the Rapid Acceleration of Diagnostics (RADx) initiative.

Signatera has been validated across multiple cancer types to detect residual disease as early as two years before standard diagnostic tools, with virtually no false positives on a per sample level, and to help assess treatment response in conjunction with imaging.

The antigen test is able to detect the presence of proteins associated with SARS-CoV-2 in 15 minutes, which is significantly faster than the standard RT-PCR test that is currently the gold standard for diagnosing COVID-19.

Sherlock’s SARS-CoV-2 test kit has received Emergency use Authorization from the FDA and is designed for use in CLIA labs certified for performing high complexity tests.

Most drugs used for COVID-19 treatments are not being used for the indication they were originally designed for and there has been much public debate about how effective or safe some of them are.

The Centers for Research in Emerging Infectious Diseases (CREID) will build a network of multidisciplinary researchers around the world to better understand how viruses and other pathogens make the leap from other living organisms to people.

Researcher at the University of Pennsylvania, carried out a computer analysis comparing exome sequencing data from 846 children with epilepsy, who had undergone genomic sequencing as part of previous studies, with phenotypic symptom data from the same individuals.