Unrecognizable businessman having chest pain and heart attack

Microbes on Tongue Could Aid Heart Failure Diagnosis

The researchers found that heart failure patients shared the same types of microorganisms in their tongue coating. Healthy people also shared the same microbes and there was no overlap in bacterial content between the two groups.

CAMP Study Reveals Unique Metabolic Signatures of Autism Spectrum Disorder

Researchers have now reproducibly identified unique metabolic signatures—called metabotypes—in more than 50% of the children from the Children’s Autism Metabolome Project (CAMP).
Bristol-Myers Squibb (BMS) plans to use Natera's Signatera custom circulating tumor DNA (ctDNA) assay in a Phase II study designed to assess the pharma giant’s cancer immunotherapy Opdivo (nivolumab) as an adjuvant treatment for non-small cell lung cancer (NSCLC). [Source: Eraxion/Getty]

Thermo Fisher Inks NSCLC CDx Deal with Daiichi Sankyo

The new co-development agreement is designed to identify non-small cell lung cancer (NSCLC) patients with human epidermal growth factor receptor 2 (HER2) mutations who may be eligible for the drug Enhertu (fam-trastuzumab deruxtecan).

New Antibody Test for COVID-19 Targets Unique Region of Spike Protein

The antibody test is based on the receptor-binding domain (RBD) of the spike protein. The RBD-based antibody test measures the levels of that domain, which the authors found correlate to the levels of neutralizing antibodies.

Sherlock, binx health Partner on CRISPR-Based, Point-of-Care COVID-19 Test

Sherlock Biosciences and binx health said they plan to develop the world’s first rapid, point-of-care diagnostic test for COVID-19 using CRISPR technology.
The American Clinical Laboratory Association has sued to block proposed 2018 Medicare payment rates for clinical tests calculated under the Protecting Access to Medicare Act (PAMA). [Source:  Clinical Center

Clinical Lab Business Picking Back Up, New Survey Says

Kalorama’s survey of labs nationwide found that currently labs are reporting a decline of 54% in lab tests other than for COVID-19, including tests for cancer, autoimmune diseases, diabetes and allergies—up from declines of 62% reported at the end of May and 82% reported on May 7.
DNA, doctor using tablet

Keeping up with the Genomes

Molecular diagnostics providers seek ways to maintain services in a world consumed by COVID-19.

RNA Imagining Shows Potential for COVID-19 Diagnostic Method

The system’s RNA aptamers act like a magnet to target and bind fluorescent dye molecules. RNA modified to contain this aptamer become excitable and glow, standing out from other parts of the cell, allowing researchers to study the RNA under a microscope.

Brain Tumor Liquid Biopsy Detects DNA Methylation Profiles

The test is based on recent work that shows that DNA-methylation profiles from plasma reveal highly specific signatures to detect and accurately discriminate intracranial tumors that share cell-of-origin lineages.

Small Sequencer Developer GenapSys Completes $90M Series C Financing

GenapSys’ sequencing system is about the size of an iPad, costs under $10,000, and is based on a proprietary direct electronic sequencing chip, which is intended to eliminate the need for cumbersome equipment.
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