Under the EUA designation, the Primerdesign test is authorized only for the detection of RNA from SARS-CoV-2 virus and diagnosis of SARS-CoV-2 virus infection, and not for any other viruses or pathogens.
The collaboration will provide a COVID-19 test offering that combines Paragon Genomics' CleanPlex SARS-CoV-2 NGS panel reagent kit for whole-genome sequencing of the coronavirus with the advanced analytical power of the SOPHiA platform.
The research reveals that the LY6E protein impairs the coronavirus’ ability to initiate infection, which could lead to treatments for the illness.
A notable addition to the effort is a team from the University of Birmingham, led by Nick Loman, Ph.D., professor of Microbial Genomics and Bioinformatics in the Institute of Microbiology and Infection, whose lab is known for fusing cutting-edge sequencing with microbial genomics.
Scripps researchers compare available genome sequence data for known coronavirus strains to determine that that SARS-CoV-2 originated through natural processes and note that their results “clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus.”
GenapSys’ sequencing system is about the size of an iPad, costs under $10,000, and is based on a proprietary direct electronic sequencing chip, which is intended to eliminate the need for cumbersome equipment.
Using computer simulations, researchers found that cavities within the altered graphene served as electrical hotspots, acting as a trap for DNA and RNA molecules, extending the time they engage with the rough graphene surface.
Hunt Willard signs on as chief science officer and VP of medical affairs, and Erica Ramos as VP of population genomics.
Emergency Use Authorization (EUA) would enable Biodesix and Bio-Rad to begin testing in the U.S. using the Droplet Digital PCR system.
“We found that the stability of SARS-CoV-2 was similar to that of SARS-CoV-1 under the experimental circumstances tested,” the authors wrote. “This indicates that differences in the epidemiologic characteristics of these viruses probably arise from other factors."