Molecular Dx

The researchers found that heart failure patients shared the same types of microorganisms in their tongue coating. Healthy people also shared the same microbes and there was no overlap in bacterial content between the two groups.

Researchers have now reproducibly identified unique metabolic signatures—called metabotypes—in more than 50% of the children from the Children’s Autism Metabolome Project (CAMP).

The new co-development agreement is designed to identify non-small cell lung cancer (NSCLC) patients with human epidermal growth factor receptor 2 (HER2) mutations who may be eligible for the drug Enhertu (fam-trastuzumab deruxtecan).

The antibody test is based on the receptor-binding domain (RBD) of the spike protein. The RBD-based antibody test measures the levels of that domain, which the authors found correlate to the levels of neutralizing antibodies.

Sherlock Biosciences and binx health said they plan to develop the world’s first rapid, point-of-care diagnostic test for COVID-19 using CRISPR technology.

Kalorama’s survey of labs nationwide found that currently labs are reporting a decline of 54% in lab tests other than for COVID-19, including tests for cancer, autoimmune diseases, diabetes and allergies—up from declines of 62% reported at the end of May and 82% reported on May 7.

Molecular diagnostics providers seek ways to maintain services in a world consumed by COVID-19.

The system’s RNA aptamers act like a magnet to target and bind fluorescent dye molecules. RNA modified to contain this aptamer become excitable and glow, standing out from other parts of the cell, allowing researchers to study the RNA under a microscope.

The test is based on recent work that shows that DNA-methylation profiles from plasma reveal highly specific signatures to detect and accurately discriminate intracranial tumors that share cell-of-origin lineages.

GenapSys’ sequencing system is about the size of an iPad, costs under $10,000, and is based on a proprietary direct electronic sequencing chip, which is intended to eliminate the need for cumbersome equipment.