One of the major scientific crusades in oncology has been to identify and validate biomarkers associated with recurrent breast cancer. [iStock / royaltystockphoto]

Agendia Reports Positive Results in IMPACt Trial for Breast Cancer

MammaPrint and BluePrint reclassified 40% of pathologically subtyped tumors, highlighting the need for an individualized, molecular subtyping profile in early stage breast cancer diagnosing for patients.
DNA research concept DNA barcodes for biomedical research  mitochondrial DNA  Prostate cancer DNA test

8 Companion Diagnostic Developers Making a Mark

If companion diagnostics (CDx) were people, they would be old enough to drink. The first CDx won FDA approval in 1998, when Dako Denmark...

Somatic Mutations at Root of Some Cancers Apparent Years Before Onset

The findings suggest that tumor development can span the entire lifetime of an individual, so the mutations that initiate cancer progression may arise decades before diagnosis.
EM Coronavirus, causing SARS

Co-Diagnostics Seeks CE Mark for its COVID-19 Coronavirus Test

The test uses the company’s CoPrimer technology to detect the presence of ribonucleic acid (RNA) of the novel strain of coronavirus in a real-time RT-PCR kit that targets conserved regions in the virus genome.
Light micrograph of metastases in breast tissue

Triple Negative Breast Cancer Recurrence Prediction Method Developed

Women whose plasma contained circulating tumor DNA had only a 56% chance of being cancer-free two years following chemotherapy and surgery, while those without it had an 81% chance the cancer would not return in the same time span.
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20 Molecular Diagnostics Companies to Watch

Up-and-Coming Diagnostic Test Developers Emerge as Consolidation Thins the Field.

CRISPR Detectives: Startups seek to expand access to diagnostics with inexpensive CRISPR-based tests

CRISPR-Cas9 is best known for its powerful ability to make double-stranded breaks in DNA, allowing scientists to delete and edit genes with relative ease....
To make better use of genomics data

Illumina and the Broad Co-Developing Open-Source Secondary Analysis Software

Leading open-source tools, GATK and DRAGEN, are being combined to create a cutting-edge software suite for methods including small variant (SNV) and large variant...
Source: Martin Barraud/Getty Images

10 Countries in 100K Genome Club

These ten governments have committed funding for projects that will sequence a minimum of 100,000 citizens to spur genomic medicine

Breast Cancer Care After Genetic Testing Often Doesn’t Follow Guidelines

Tracking treatment trends is important as more women are receiving genetic testing when they are diagnosed with early-stage breast cancer and treatment options are expanding.
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