The power of new sequencing technologies is their ability to unlock information about the variable nature of solid tumors to provide clinicians with a better understanding of cancer’s mechanisms. [© Monika Wisniewska/Fotolia]

Next-Generation Sequencing at the Heart of Personalized Cancer Treatment

There is little doubt that the future of solid tumor cancer treatment will be increasingly precise and tailored to individual patients based on specific...
One novel technique for capturing clinically important low-abundance proteins is to create core-shell hydrogel nanoparticles containing high affinity reactive chemical baits for protein and peptide harvesting and concentration. [AlexRaths/iStock Photos]

Challenges Remain in MS-based Proteomic Analysis of Complex Biological Samples

Many scientists point out that it’s become clear there are no simple universal strategies for the comprehensive analysis of complex proteomes. Although the application...
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Roche Nabs AbVitro’s PETE Technology to Support Clinical NGS

Roche has picked up exclusive rights to AbVitro's primer extension-based target enrichment (PETE) technology and associated patent applications AbVitro has filed. The technology, Roche...
Figure 1. Method of sequencing samples from a JAK2-negative myeloproliferative neoplasm patient

Single-Cell Approach to Personalized Medicine

As one of the most prevalent causes of death across the globe, the burden of cancer is still sharply increasing, predominantly due to the...
Experts have suggested that in the next decade large-scale sequencing for all healthy babies at birth is plausible. [Source: © Miroslav Beneda - Fotolia.com]

Newborn Screening: Adapting to Advancements in Whole-Genome Sequencing

Since 1963, state public health programs have screened newborns for a number of life-altering health conditions. Many of these disorders are rare and genetic,...
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How Much Genetic Information Is Too Much Information?

As the genomic age takes hold, the medical and pharmaceutical industries are just now beginning to scratch the surface of innovation in testing for...
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FDA Issues Draft Guidance on LDTs

The FDA today issued draft guidance detailing its plans for regulating laboratory-developed tests (LDTs) that it deems as “high-risk” along the lines of Class...
The IVD market is segmented into clinical chemistry

Multifaceted IVD Market Growing Rapidly

In vitro diagnostics (IVD) are a prominent and fast emerging segment of the global healthcare sector. IVD tests analyze human samples such as blood,...
Figure 1. Overview of the bioinformatics steps for NGS sequencing data

Investigator-Completed NGS Data Analysis

While sequencing entire human genomes is an important achievement of next-generation sequencing (NGS) technology, many clinical research goals can be achieved by sequencing a...
CombiMatrix

Microarray Testing for Unmet Needs

CombiMatrix, a CLIA-certified laboratory, is bringing microarray analysis to the underserved problem of recurrent pregnancy loss as well as to prenatal testing. CombiMatrix performs...
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