Comprehensive molecular profiles of the most common cancer types are now available. [NHGRI]

The Future of Cancer Genomics

As you have probably noticed, there’s been a major shift in the focus of next-gen sequencing over the past couple of years. First it...
Source: iStock/Mutlu Kurtbas

Point-of-Care Molecular Diagnostics Evolve

As described by the National Institutes of Health (NIH), point-of-care (POC) instruments combine multiple analytical functions into self-contained, portable devices that can be used...
Source: iStock/fatido

Costs of Genome Sequencing in the Clinic Tend to Peak Early

When genomic sequencing is added to a patient’s care, the initial costs can be considerable, but they don’t appear to climb over time. For...

Exome Sequencing Identifies Possible Mutations Linked to Bipolar Disorder

Researchers have identified 84 potential inherited gene mutations that may contribute to the most severe forms of bipolar disorder.
The first printout of the human genome as displayed at the Wellcome collection

The Value of Present and the Promise of Future Sequencing Strategies

The Human Genome Project provided a path for determining the genetic basis of many inherited diseases and neoplasms. So far, various efforts from both...
Source: © inkaone -

FDA Issues Draft Guidance on LDTs

The FDA today issued draft guidance detailing its plans for regulating laboratory-developed tests (LDTs) that it deems as “high-risk” along the lines of Class...
Harmonizing NGS standards is expected to provide a strong evidence base for decisions on coverage of clinical genomic testing and treatment for cancer. [iStock / zmeel]

Harmonizing Standards for NGS Registries and Databases

The Green Park Collaborative (GPC) and the Molecular Evidence Development Consortium (MED-C) are launching a joint effort to advance personalized medicine by harmonizing standards...
Source: Union of Concerned Scientists

Effects of NIH Budget Cuts Will Extend into the Clinic, Kalorama Cautions

Long-term effects seen beyond FY2018 if reduced federal spending slows down the transformation of research into clinical practice
Source: Andrzej -

Maximizing the Efficacy of Genetic Testing

Genetic counseling services provider InformedDNA released today a white paper on genetic testing. Use of these diagnostic tests is growing rapidly, but inappropriate testing...
A new method has been developed to analyze DNA "in the wild." It could save researchers months of toil. The ultimate goal is to build a comprehensive database of the thermal behaviors of DNA and RNA strands. [Cindy Thaung/Rice University]

Molecular Diagnostics on Thermal Tracks of “DNA in the Wild”

Before they can design diagnostic reagents that can recognize specific bits of DNA and RNA, scientists typically resort to a kind of tracking. While...
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