Precision Medicine

Beta-blockers such as propranolol have an anti-inflammatory effect in cancer that could be used to target the extreme inflammation seen in severe cases of COVID-19.

A gene mutation in the cystic fibrosis gene may explain why some people with Duchenne Muscular Dystrophy experience cardiomyopathy at an earlier stage to others according to research from the University of Texas Southwestern Medical Center.

ARGONAUT is a longitudinal, prospective, observational study that will enroll advanced-stage cancer patients of diverse racial backgrounds to collect data to both inform the development of precision microbiome medicines and to identify needed companion diagnostics to guide treatments.

Low-level interferon signaling that offers antiviral protection in the absence of active infection is present in all humans shortly after birth, but where and how this signaling occurs has remained unclear. The newly reported work offers up an explanation for this phenomenon.

An artificial neural network can accurately predict the prognosis of melanoma patients based on pre-treatment histology images, shows research led by the NYU Grossman School of Medicine.

Using a combination of proteomic analyses and DNA and RNA sequencing to profile breast cancer tumors could lead to more effective, tailored treatment, suggests research from the Broad Institute and Baylor College of Medicine.

The research suggests the nature and outcome of medulloblastoma relapse are biology and therapy dependent, providing translational opportunities for improved disease management through ongoing surveillance, prognostication, and risk-stratified selection of second-line treatments.

If companion diagnostics (CDx) were people, they would be old enough to drink. The first CDx won FDA approval in 1998, when Dako Denmark...

10 privately-held diagnostics developers primarily focused on liquid biopsy tests, ranked by total money raised from venture capital firms.

The study could signal a potential treatment breakthrough for patients with this form of breast cancer, which disproportionately affects and tends to develop more aggressively in black women.