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DiamiR Wins $2.75M NIA SBIR Grant Toward Alzheimer’s Diagnostic

DiamiR’s CogniMIR test is designed to detect Alzheimer's at the presymptomatic, mild cognitive impairment and dementia stages
Boy using Inhaler for asthma

Almost 3X as Many Genes Associated with Childhood Asthma as Adult Asthma

Researchers report that a genome-wide association study (GWAS) demonstrated that childhood-onset asthma was associated with nearly three times as many genes as adult-onset asthma....
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Novel Genome Screen Uncovers Microbial Drug-Resistance Mutations

Among the 76 newly discovered mutations are several that provide bacteria with the ability to degrade carbapanems, a class of antibiotics
The NCI is funding research to determine whether outliers from failed clinical trials can reveal hidden drug development possibilities. [iStock/francisblack]

Exceptional Responders: The “N of 1” Paradigm

We have all heard stories about the single patient who survives a deadly cancer in response to a particular drug, in contrast to other...
Clinical OMICs Magazine: Volume 5

The Promise of Panomics: Decoding Biological Networks to Identify Pathways Involved in Complex Diseases

Technological advances such as high-throughput sequencing are transforming medicine from symptom-based diagnosis and treatment to personalized medicine as scientists employ novel rapid genomic methodologies...
Novartis’ Kymriah™ (tisagenlecleucel) will be the first chimeric antigen receptor T-cell (CAR-T) cancer immunotherapy to reach the U.S. following FDA approval yesterday [Source: Novartis]

FDA Approves Novartis’ Kymriah As First CAR-T Cancer Immunotherapy

Novartis’ Kymriah (tisagenlecleucel) will be the first chimeric antigen receptor T-cell (CAR-T) cancer immunotherapy to reach the U.S.
New data describes the economic impact of genomic sequencing procedures. [NIH]

Microsoft, Jackson Labs Collaboration Creates Precision Medicine Database

The collaboration will curate JAX’s Clinical Knowledgebase (CKB), a searchable database where subject matter experts store, sort, and interpret complex genomic and other data that can be used to improve patient outcomes.
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Crick Researchers: Ras Mutations also Boost Tumor Immunoresistance

Responsible for 25% of all human cancers, the Ras gene also helps cloak cancer cells from the immune system by boosting PD-L1 expression
Clinical OMICs Magazine: Volume 1

Using Genomics to Prevent Cancer

Genetic Alliance, in partnership with the Centers for Disease Control’s Office of Public Health Genomics, has released a set of videos to share information...
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CRISPR Gene Editing Can Introduce Hundreds of Unintended Mutations

Columbia University findings present cautionary tale amidst accelerating use of CRISPR-Cas9 for research and therapeutic development.
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