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New research examines why some children born with heart defects also have developmental disabilities. [Image courtesy of Mark L. Riccio
New consensus statements have been released on using platelet function/genetic testing to decide antiplatelet treatment after percutaneous coronary intervention (PCI). As different P2Y12receptor inhibitors (i.e. clopidogrel, prasugrel, and ticagrelor) have been approved for post-PCI treatment more physicians have started prescribing individualized regimens.  An international expert panel’s updated recommendations for such prescribing were recently published in JAAC: Cardiovascular Interventions. PCI is one...
IsoPlexis has won a $4 million grant from the National Cancer Institute (NCI)'s Small Business Innovation Research (SBIR) Development Center toward commercializing its IsoLight single-cell, secreted protein analysis system. Based in Branford, CT, IsoLight is a precision engineering platform designed for research use only in CAR-T therapy product evaluation, quality check pre-infusion, and correlative studies to understand and characterize differences...
Johnson & Johnson’s Janssen Research & Development will use BiomX's XMarker platform to discover microbiome-based biomarkers for inflammatory bowel disease (IBD)
Diffuse, widespread, and chronic pain, such as that caused by fibromyalgia, is often frustratingly difficult to understand. Concentrating on the gut, however, may yield new insights. It may even simplify the diagnosis of notoriously hard-to-pin-down conditions. This would be welcome news to fibromyalgia patients, who can endure long waits—four to five years—before receiving a final diagnosis The gut, or more...
A liquid biopsy test has detected changes in the BRCA1 or BRCA2 genes associated with ovarian and breast cancer that signal when the disease stops responding to treatment through platinum chemotherapy or poly ADP-ribose polymerase (PARP) inhibitors. [Source: © freshidea/Fotolia]
Scientists at Uppsala University and the Sahlgrenska Academy, University of Gothenburg say they have developed a blood test that may provide a more precise diagnostic for suspected ovarian cancer that would eliminate the need for exploratory surgery. This could lead to a reduction in unnecessary surgery and to earlier detection and treatment for affected women, noted the researchers whose...
MGI Tech (MGI), a subsidiary of BGI Group, and Centre for Translational Microbiome Research (CTMR) at Karolinska Institutet, Stockholm today announced a strategy collaboration in microbiome research and initiated the 10,000 Metagenomics Project as phase one project. The joint-research project is leading by Professor Lars Engstrand and Professor Mathias Uhlén, supporting by Karolinska Institutet and Ferring Pharmaceuticals, using MGI’s...
Seamless pattern of hand drawn faces of various ethnicities
Researchers analyzed DNA from nearly 50,000 people of non-European decent and found 27 new genetic variants associated with chronic diseases, including high blood pressure, type 2 diabetes and kidney disease. They also looked at genetic associations with behavior, finding variants associated with daily smoking and coffee drinking habits. The goal of the study was to understand how disease risk...
Diagnostic firms are working to create new tests that can detect rheumatoid arthritis earlier and also provide risk assessment profiles of patients that are more or less likely to suffer permanent physical damage as a result of the disease. [©Puwadol Jaturawutthichai/Shutterstock]
Researchers part of a public-private partnership have identified new targets for the treatment of autoimmune diseases, including lupus and rheumatoid arthritis. That’s according to a trio of new studies published in the 18 June 2019 issue of Nature Immunologythat provide new details about how tissue damage occurs in these diseases. No effective targeted therapy currently existsfor systemic lupus erythematosus (lupus)...
Close-Up Of Woman Smoking Weed
Researchers from the Danish psychiatric project (iPSYCH) report that they have found a specific gene that is associated with an increased risk of cannabis abuse. The gene is the source of a so-called nicotine receptor in the brain, and people with low amounts of this receptor have an increased risk of cannabis abuse. “We discovered that the disorder was associated...
Illumina said it has won a decision in a U.K. patent court which sided with the company in ruling that one of its patents was infringed by Roche-owned Ariosa Diagnostics and The Doctors Laboratory (TDL) in the methodology of a non-invasive prenatal test (NIPT). The High Court of Justice, Chancery Division, Patents Court issued a judgment on Monday finding that...
Smiling Beagle
A dog’s sense of smell—more than 10,000 times more sensitive than that of our own—has been exploited by humans for centuries. Whether it is finding hikers and skiers buried by avalanches in the Alps, or helping sniff out contraband drugs, the olfactory talents of man’s best friend are well known. More recently, dogs have been recognized for being able to...
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