Researchers at the Sidney Kimmel Cancer-Jefferson Health say their investigation indicates that the circadian clock gene CRY1 promotes tumor progression by altering DNA repair and could represent a new therapeutic target for prostate cancer.
Normally, confirming a pneumonia diagnosis requires growing bacterial samples from patients in a lab, which is time-consuming. The new test can identify 52 different pathogens, and can be done in around four hours, without needing to grow the bacteria.
Research suggests that a build-up of abnormal microRNAs could be behind the increased risk for Alzheimer’s disease seen in patients who have experienced traumatic brain injury.
The new IDP consists of 30 different specificities targeting most major immune markers, conveniently grouped together in a single tube.
The researchers trained a natural language processing model to analyze patterns found in genetic sequences, which allowed it to predict new sequences that have new functions but still follow the biological rules of protein structure.
The study shows that endogenous mis-spliced RNA in tumor cells mimics an RNA virus, leading tumor cells to self-destruct as if fighting an infection.
Research explains how mutations in the RUNX1 gene, which encodes a protein that guides the way hematopoietic stem cells change into adult blood cells, can influence blood cell development and cause different types of cancer and other blood disorders.
In studies of a group of 171 heart transplant recipients, the new blood test performed better than tissue biopsies, signaling problems even when no outward signs of rejection were evident.
Tandem repeat mutations, found in non-coding areas of the DNA, could be linked to the presence of autism spectrum disorders, according to University of California researchers.