A genetic variant in the fibronectin 1 gene conveys significant protection against Alzheimer's disease in high risk APOE4 homozygotes.
More than half of cancer drugs granted accelerated approval between 2013 and 2017 did not demonstrate a significant improvement in overall survival (OS) or quality of life (QoL) within five years of approval, shows an analysis of U.S. Food and Drug Administration (FDA) data.
Saruparib showed favorable safety profile over first-generation PARP inhibitors in Phase I/II trial.
Diagnostics company BillionToOne, a developer of liquid biopsy tests in oncology will partner with Culmination Bio to validate two of its oncology diagnostic tests.
Scientists published a commentary describing the theoretical best time to initiate targeted therapy with APOBEC inhibitors.
Scientists from the Tufts University School of Medicine, in collaboration with other scientific institutions, have introduced a promising compound, UH15-38, showing the potential to significantly relieve lung damage and inflammation caused by the flu virus.
Investigators at the Murdoch Children’s Research Institute (MCRI) say they have discovered a blood protein biomarker that could help detect which children will experience ongoing concussion symptoms more than two weeks after the initial injury.
Coronary artery disease and major depression may be genetically interconnected via inflammatory pathways.
An artificial intelligence based generative adversarial network can speed up retinal imaging almost 100-fold and improve image quality.
Microbes within metastatic cancer tumors could impact the efficacy of immunotherapy, research has revealed, with one bacterium in particular linked with poor outcomes for lung cancer.