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CRISPR technology

Top 600 Cancer Drug Targets Ranked Using CRISPR

Researchers from the Wellcome Sanger Institute, GlaxoSmithKline, EMBL-EBI, and Open Targets conducted one of the largest CRISPR screens of cancer genes to date.
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Algorithm IDs Cancer Patients for Precision Treatments by Decoding Mutational Signatures

A new algorithm analyzes patterns in mutational profiles to identify cancer patients with underlying defects in DNA repair machinery, guiding targeted therapies.

Sophia Genetics Gains CE-IVD Marking for Solid Tumor Solution

Sophia Genetics has obtained the CE-IVD marking for its Solid Tumor Solution (STS), a molecular diagnostic application designed to precisely detect and characterize all...
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Top 10 Sequencing Companies

Five years after the introduction of the $1,000 genome, the sequencing field remains rife with chatter about pushing the cost much lower—not only to $100...
Prostate cancer cells, illustration

Helomics, SpeciCare Enter Live Tumor Tissue Precision Cancer Care Collaboration

Helomics will provide CRO services and its D-CHIP artificial intelligence (AI) platform for a functional precision medicine study called PIONEER sponsored by SpeciCare.

Flatiron Health, Foundation Medicine Publish Study Validating Clinico-Genomic Database

The study validates that real-world data obtained from routine clinical care to create a multi-institution clinico-genomic database can yield clinically meaningful insights.
Colon cancer. Cancer attacking cell. Colon disease concept

CRC Evades Immunotherapies by Regulating Expression of Cell Surface Molecule

CRC tumors can switch off expression of a cell surface molecule that is a key target of immunotherapy, thus preventing the treatment from working.
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AI IDs Potentially Life-Threatening Genetic Disease Using EHRs

The classifier could help to flag patients who are most likely to have familial hypercholesterolemia, so that they and their families can undergo further genetic testing.

DNAnexus, UPMC, Sutter Health Launch Clinico-Genomic MS Precision Medicine Study

Clinico-genomic research study aims to improve personalized treatments for people with multiple sclerosis DNAnexus, UPMC, and Sutter Health network said today they have launched a...

Stanford Studies Feasibility of AI Platform for Blood Cancer Precision Treatments

The AI platform from Notable completed personalized treatment recommendations for all 20 patients within 30 days demonstrating both a positive and negative predictive value average of 84 percent.

Evotec, Individumed Partner on Precision Medicine for Colorectal Cancer

Evotec and Individumed said today they will partner to develop new precision therapeutics for colorectal cancer (CRC), through a collaboration whose value was not...

Non-Invasive Prenatal Screening Test

HDPCR Tick-Borne Pathogen (TBP) Panel is a multiplexPCR test that detects nine of the most common tick-borne pathogens in a single test.

Wearable Data Revolution

There is no doubt the age of wearable monitors is upon us. Sales of physical activity monitors have increased dramatically from 15 million in...

Generate PCR-Amplified cDNA Libraries

HDPCR Tick-Borne Pathogen (TBP) Panel is a multiplexPCR test that detects nine of the most common tick-borne pathogens in a single test.
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20 Molecular Diagnostics Companies to Watch

Up-and-Coming Diagnostic Test Developers Emerge as Consolidation Thins the Field.
Clinician Offering Drugs Based On DNA Profiling

FDA Sends Warning Letter to Inova Over Pharmacogenomics Test

The agency said it is unaware of data establishing that Inova’s tests helps patients or clinicians make appropriate treatment decisions for the listed drugs.
Projections for the growth of the liquid biopsy market range as low as $1 billion by 2020

10 Liquid Biopsy Companies in the Money

10 privately-held diagnostics developers primarily focused on liquid biopsy tests, ranked by total money raised from venture capital firms.
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10 Countries in 100K Genome Club

These ten governments have committed funding for projects that will sequence a minimum of 100,000 citizens to spur genomic medicine

Five-Year Super Successes in Genomics and Precision Medicine

Multidimensional, computationally rich approaches represent the next wave of innovation, taking personalized medicine to the next level, while demanding more of practitioners, who in...

PerkinElmer, Helix Partner to Launch Genetic Screening Test

The DNA test available to healthy individuals analyzes all 59 medically actionable genes identified by the American College of Medical Genetics and Genomics.
Ambry Genetics and My Gene Counsel said they will partner to offer medical-grade testing designed to confirm results of direct-to-consumer (DTC) genetic tests

Ambry and My Gene Counsel Team Up on Tests to Confirm DTC Results, Counseling

Program designed for consumers who have taken a DTC genetic test, have a personal or family history of cancer and have unresolved questions.
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First AAV-Delivered Gene Therapy for Inherited Disease Approved by FDA

The FDA approval is the third for a gene therapy, but is the first approval for a treatment using adeno associated viral vector delivery
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Top 15 Molecular Diagnostics M&A Deals of 2016

Molecular diagnostics accounts for only a tenth of the in vitro diagnostics (IVD) market—but most of its hopes for future revenue growth.

Lack of Diverse Ancestry Data Hinders Polygenic Risk Scores

A new study shows PRSs developed by studying Europeans do a better job at predicting disease risk for people of European ancestry than for those of other ancestries
Myriad Genetics' myChoice HRD Plus test will be used by AstraZeneca in an exploratory analysis to identify women with advanced ovarian cancer who may benefit from maintenance treatment with a combination of AZ’s Lynparza® (olaparib) and the Genentech (Roche) cancer drug Avastin® (bevacizumab). [Source: OGphoto / Getty Images]

AZ to Use Myriad’s myChoice HRD Plus Test in Phase III Trial

Myriad Genetics will use myChoice HRD Plus to evaluate patients enrolled in an ongoing Phase III trial, in order to identify HRD cases
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