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COVID-19 Patients May Carry Virus after Symptoms Have Resolved

The study found that the incubation period of the virus was five days for all but one of the patients, and the average duration of symptoms was eight days. However, the length of time that patients remained contagious after resolution of their symptoms ranged from one to eight days.
Doctor holding oxygen ambu bag over patient given oxygen to patient by intubation tube in ICU/Emergency room

ACE inhibitors and Angiotensin Receptor Blockers May Increase Mortality Rate In Elderly COVID-19 Patients

These highly prescribed medications change cell surface protein expression, which is particularly problematic in cells in the respiratory system—tissue that is vulnerable to targeting and attack by the COVID-19 virus.
Coronavirus Covid-19 Vaccine

Moderna Charts Fast Track of SARS-CoV-2 Vaccine to Clinical Trials

As Moderna's vaccine development moves at unprecedented speed, the company's CEO explains how they have moved so quickly and why he is hopeful that their pace will continue.
I better not be getting sick

Stanford Researchers Dig Into Community Spread of COVID-19

The researchers explain why it is an urgent matter for environmental engineers and scientists to collaborate on pinpointing viral and environmental characteristics that affect COVID-19 transmission via surfaces, the air, and fecal matter.

Abbott Launching ID NOW COVID-19 Tests, Offering Positive Results in Five Minutes

Company expects to deliver 50,000 tests per day of the rapid, instrument-based, isothermal system designed for qualitative detection of infectious diseases.
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Prototype Tool Leverages AI to Predict Which COVID-19 Patients Most Likely to Develop Severe...

The tool indicated that a combination of small changes in levels of the liver enzyme alanine aminotransferase (ALT), patient-reported myalgia (aching muscles), and raised hemoglobin levels, most accurately predicted the development severe disease.
Myanmar: Rhesus Macaque

New Study Suggests COVID-19 Reinfection Unlikely

The study used four adult Chinese rhesus macaques and found that those monkeys that had been re-exposed to SARS-CoV-2, like the unexposed control monkey, showed no recurrence of COVID-19.

COVID-19 Symptom Checker for Individual Monitoring

COVID-19 Compass is based on CDC guidelines, best clinical practices, illness severity, and risk factors such as age, gender, location, potential exposure and pre-existing health conditions.

Largest Study to Date of COVID-19 Susceptibility Launched

Researchers will launch the study involving 1,000 subjects—consisting of COVID-19 patients and their partners and first-degree relatives as controls—to compare a variety of genomic and other biological variables between those patients who show no or mild symptoms and those who show severe illness.

New Institute to Seek AI-Based Solutions to Curbing COVID-19 Pandemic

C3.ai DTI will focus its research on AI, machine learning, the internet of things, big data analytics, human factors, organizational behavior, ethics, and public policy.

Sophia Genetics, Paragon Genomics Team on SARS-CoV-2 Testing

The collaboration will provide a COVID-19 test offering that combines Paragon Genomics' CleanPlex SARS-CoV-2 NGS panel reagent kit for whole-genome sequencing of the coronavirus with the advanced analytical power of the SOPHiA platform.

Scientists Uncover Protein that Inhibits Coronaviruses

The research reveals that the LY6E protein impairs the coronavirus’ ability to initiate infection, which could lead to treatments for the illness.
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Novacyt COVID-19 Diagnostic Gains FDA Emergency Use Authorization

Under the EUA designation, the Primerdesign test is authorized only for the detection of RNA from SARS-CoV-2 virus and diagnosis of SARS-CoV-2 virus infection, and not for any other viruses or pathogens.
Human papilloma virus, illustration

Biomarker of Female Precancer Risk from HPV Found in Microbiome

Gardnerella bacteria were the dominant biomarker for the progression of HR-HPV and its effect is mediated by increased cervicovaginal bacterial diversity directly preceding the progression of a persistent infection to precancer.
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The Clinical OMICs 10 Under 40

From polygenic risk scores and CRISPR to immune therapies and mapping human cells, our inaugural selection of young scientists underscores the breadth of precision health research.
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U.K. to Use Nanopore Sequencing to Map COVID-19 Spread

A notable addition to the effort is a team from the University of Birmingham, led by Nick Loman, Ph.D., professor of Microbial Genomics and Bioinformatics in the Institute of Microbiology and Infection, whose lab is known for fusing cutting-edge sequencing with microbial genomics.

Triple negative breast cancer might not actually be ‘breast cancer’

The study could signal a potential treatment breakthrough for patients with this form of breast cancer, which disproportionately affects and tends to develop more aggressively in black women.
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Genetic Study Shows Coronavirus Evolved Naturally, Is not Lab-Constructed

Scripps researchers compare available genome sequence data for known coronavirus strains to determine that that SARS-CoV-2 originated through natural processes and note that their results “clearly show that SARS-CoV-2 is not a laboratory construct or a purposefully manipulated virus.”

Small Sequencer Developer GenapSys Completes $90M Series C Financing

GenapSys’ sequencing system is about the size of an iPad, costs under $10,000, and is based on a proprietary direct electronic sequencing chip, which is intended to eliminate the need for cumbersome equipment.
3d rendered ovarian cancer illustration.

Ovarian Cancer Cells’ Dependence on Fat Suggests New Therapeutic Target

The enzyme Carnitine Palmitoyltransferase 1A (CPT1A) may control how much fat ovarian cancer cells can burn, suggesting a treatment that limits these cells’ access to CPT1A may starve them of the resources they need to spread.
Abdomen with Bulls Eye

Immunotherapy Success Determined by Gut Microbiome

Using mouse models of malignancy, researchers at UT Southwestern Medical Center and the University of Chicago have implicated the gut microbiome in the success of immunotherapies. The researchers suggest that gut bacteria can penetrate tumor cells and boost the effectiveness of an experimental immunotherapy that targets the CD47 protein.

Biodesix, Bio-Rad Pursue FDA EUA Approval for ddPCR-Based COVID-19 Test

Emergency Use Authorization (EUA) would enable Biodesix and Bio-Rad to begin testing in the U.S. using the Droplet Digital PCR system.
ArcherDX said its Archer Immunoverse and VariantPlex NGS assays will be used by Ambry toward offering its biopharma customers large-scale immune repertoire analysis and chimeric antigen T-cell receptor (CAR-T) manufacturing characterization and pharmacodynamics. [royaltystockphoto/Getty Images]

Removing EGR4 “Brake” on Immune Activation May Be Viable I/O Therapeutic Approach

New research demonstrates that taking EGR4 away promotes the activation of killer T cells, which infiltrate and attack tumors and thereby boost anticancer immunity.
Coronavirus

Cepheid, Sherlock to Develop Coronavirus Test, Part of Broader MDx Collaboration

The companies will partner on a proof-of-concept project focused on detection of SARS-CoV-2 coronavirus as the first initiative of a broader collaboration focused on developing molecular diagnostic tests for infectious diseases and oncology.
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Ex-Geisinger Principals Team with Genome Medical to Expand Genetic Services

Hunt Willard signs on as chief science officer and VP of medical affairs, and Erica Ramos as VP of population genomics.
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