Sponsor: Thermo Fisher Scientific


The Ion Torrent Oncomine Myeloid Research Assay is a new, targeted next-generation sequencing (NGS) research panel for simultaneous analysis of 74 relevant genes. It allows interrogation of DNA mutations, RNA fusion transcripts, and gene expression levels associated with myeloid cancers in a single run, yielding results in two to three days. The assay is designed to analyze 40 DNA genes, 29 fusion driver genes, and five gene expression levels associated with several myeloid cancers, including:

  • acute myeloid leukemia (AML)
  • myeloid dysplastic syndrome (MDS)
  • myeloproliferative neoplasm (MPN)
  • chronic myeloid leukemia (CML)
  • chronic myelomonocytic leukemia (CMML)
  • juvenile myelomonocytic leukemia (JMML)

The assay workflow is simplified with the Ion Chef System for library preparation. In addition, access to the Oncomine Knowledge Reporter allows users to link variants to relevant labels, guidelines and global clinical trials.

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